An acceleration experimental design method for hybrid-lubrication conformal-contact surface tribological evolution was proposed. The method was based on the concept of “viscosity-reduction acceleration”, where the asperity contact states were preserved while the evolution of tribological behavior was accelerated by increasing the interaction frequency between surface asperities. The approach was validated by Plint TE-92 friction and wear tester.The results show that at the non-accelerated condition (sliding speed is as 0.2 m/s, temperature is as 25 °C, duration is as 20 min) and the corresponding accelerated condition (sliding speed is as 0.4 m/s, temperature is as 47 °C, duration is as 10 min) share the highly consistent values of friction coefficient, and 3D surface parameters Sq and Ssk. It indicates that the wear effect of 10-minute in test with accelerated parameters is equivalent to that of 20-minute in test with non-accelerated parameters.