The importance and the reliability sensitivity of the correlation coefficients among the basic variables in generalized random space in the reliability analysis were investigated. By the reliability analysis optimal method including operation of the correlation coefficients among the basic random variables in generalized random space, the importance of the correlation coefficients among the basic variables in generalized random space in the reliability analysis was analyzed through calculation of the reliability analysis, and the influence of the correlation coefficients among the basic variables in generalized random space on the structural reliability through calculation of the reliability sensitivity. The method can be used to obtain information such as the importance of the correlation coefficients among basic variables in generalized random space, influence and different influence levels on the structural reliability. Some useful reference to statistical work and reliability design is provided.